The National Toxicology Program has released the Peer Review Report documenting the proceedings and recommendations of the peer reviewers at the National Toxicology Program Peer Review Meeting of the Draft NTP Technical Reports on Cell Phone Radiofrequency Radiation held March 26–28, 2018 at the National Institute of Environmental Health Sciences Research Triangle Park, NC.
At the end of the March 26–28, 2018 Peer review meeting the experts reviewers voted to increase the level of confidence for seven tumor types. The malignant schwannomas found in male rats were deemed “clear evidence” of cancer. The malignant gliomas in the brain, and pheochromocytoma in the adrenal medulla (GSM only) of male rats were deemed “some evidence” of cancer. Increased right ventricular cardiomyopathy in the heart was found in the exposed groups. In addition, several other tumors were increased in the exposed groups and DNA damage was found in various organs.
Download the NIEHS/NTP Peer Review Report
Download NIEHS/NTP issued PDF of Peer Reviewers Conclusions
Download Presentation by Dr. Michael Wyde NTP Summarizing the NTP
On June 20, 2018 Drs. Chad Blystone and Michael Wyde made presentations to the NTP’s Board of Scientific Counselors Meeting that summarize the study findings.
“At the end of the 2-year studies, increased incidences were observed in malignant schwannomas and right ventricular cardiomyopathy in the heart, malignant gliomas in the brain, and pheochromocytoma in the adrenal medulla (GSM only) of male rats. A number of neoplastic lesions were also observed that were considered equivocal findings that may have been related to RFR exposure in male (brain (granular cell tumors), pituitary gland, prostate, liver, adrenal gland, and pancreas) and female rats (heart, brain, and adrenal gland)”
“In the rat studies, exposures were initiated in utero and consistently resulted in exposure concentration-related decreases in pup body weight and body weight gains during the perinatal period. In general, decreased pup survival was observed at the higher levels of RFR tested. Increased DNA damage in cells of the hippocampus and frontal cortex was observed in RFR-exposed male mice from the CDMA study.”
“The primary finding observed in mice in these studies was increased DNA damage in cells of the frontal cortex of RFR-exposed male mice (both GSM and CDMA). This finding was not associated with any change in brain tumors in the 2-year studies; however, elevated incidences of neoplastic lesions were observed in male (skin and lung) and female mice (malignant lymphomas).”
-Summary of findings by Dr. Michael Wyde
presented to Board of Scientific Counselors in June 2018 Meeting
What were the conclusions of the expert peer reviewers?
On March 26-28, 2018 the expert peer review panel voted on the following recommendations.
Evidence of Carcinogenicity in Rat Studies
The following tumor endpoints were voted as “ equivocal” as there was a marginal increase of neoplasms that may be related to the exposure.
Equivocal findings from studies on rats exposed to cell phone RFR at 900 MHz
Equivocal findings from studies on mice exposed to cell phone RFR at 1,900 MHz
Regarding the increases in nonneoplastic lesions found after exposure, the panel voted to accept unanimously the following:
* The peer reviewers recommended an elevated conclusion for seven cancer endpoints. Thus their classification was increased to a higher level of confidence (than was stated in the 2/2018 issued draft reports) as to the association between the RFR exposure and cancer.
Note on DNA Damage found in the NTP
DNA damage was significantly increased in the frontal cortex of male mice (both modulations GSM and CDMA), peripheral leukocytes of female mice (CDMA only), and hippocampus of male rats (CDMA only). “These results suggest that exposure to RFR has the potential to induce measurable DNA damage under certain exposure conditions,” stated the NTP scientists in this PDF presentation (9/2017) of the NTP Genotoxicity findings.
PDF presentation (9/2017) of the NTP Genotoxicity DNA Damage findings.
ADDITIONAL RESOURCES
The News and Observer News Article “Can your cellphone cause cancer? Scientists find definitive link in study of rats.”
Scientists Recommend Stronger Indications of RF Causing Tumors in Rats, Radio Resource International Magazine
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